Nerves:
(see Deficiency or Essential
Fatty Acids)
Nitric Oxide
Nerves: (see Deficiency
or Essential Fatty Acids)
Omega-6 fatty acids are key structural components of cell membranes,
and are an integral part of the myelin sheath, which protects nerves.
Reference: Present Knowledge in Nutrition, Intl Life
Sciences Foundation, July 1990, pp 63., ISBN: 093536840X
An
EFA deficiency causes our nervous system to suffer.
Nitric Oxide
Study: "The
Effects of Nitric Oxide on Rat Aortic Smooth Muscle in vitro,"
examined the effects of nitric oxide (NO) and phenylephrine (PHE) on
isolated rat aortic rings in smooth muscle bath preparation. PHE (10
-5 M) was initially applied to all tissues to provide a control contractile
response. When nitric oxide (10 -5 M) was applied to tissues, relaxation
always occurred. When PHE was reapplied after NO had been administered,
a contractile response was observed, similar to that of the initial
response to PHE. When NO was applied to a tissue that had been pre contracted
with PHE, a relaxation of the tissue was observed again. These results
indicate that NO has a relaxing effect on aortic tissue, and may play
an important role in the management and regulation of blood pressure.
References: Dodd-o, J.M., G. Zheng, H.S. Silverman,
E.G. Lakatta and R.C. Ziegelstein. 1997. Endothelium-independent relaxation
of aortic rings by the nitric oxide synthase inhibitor diphenyleneiodonium.
Br. J. Pharm . (120): 857-864.
Forte, P., M. Copland, L.M. Smith, E. Milne, J. Sutherland, and N. Benjamin.
1997. Basal nitric oxide synthesis in essential hypertension. Lancet
349(9055): 837-842.
Fujimoto, S. and T. Itoh. 1997. Role of nitric oxide and nitric oxide-independent
relaxing factor in contraction and relaxation of rabbit blood vessels.
Europ. J. Pharm . 330: 177-184.
Griffiths, C., C. Bon, and J. Garthwaite. 1998. Nitric oxide in CNS
physiology and pathology. Neurotransmissions 14(1): 3-10.
Huang, Y., C.W. Lau, F.L. Chan, and X.Q. Yao. 1999. Contribution of
nitric oxide and K +channel activation to vasorelaxation of isolated
rat aorta induced by procaine. Europ. J. Pharm . 367: 231-237.
JMP Statistics and Graphics Guide. Version 3. 1994. SAS Institute Inc.,
Cary, NC.
Kanagy, N.L., J.R. Charpie, J. Dananberg, and R.C. Webb. 1996. Decreased
sensitivity to vasoconstrictors in aortic rings after acute exposure
to nitric oxide. Amer. J. Physiol . 271 (Heart Circ. Physiol. 40): H253-H260.
Okawa, T., A.S. Syal, Y.P. Vedernikov, G.R. Saade, K. Chwalisz, R.E.
Garfield. 1998. The effects of nitric oxide on the contractility of
isolated uterine and aortic rings from pregnant rats. Amer. J. of Ob.
and Gyn . 179(3): 721- 726.
Research Biochemicals Incorporated. 1999 Catalog. RBI/Sigma: A member
of the Sigma-Aldrich Family of Companies. Natick, MA.
Umans, J.G. 1997. Less nitric oxide, more pressure, or the converse?
Lancet 349(9055): 816-817.
Niacin
Overdoes Information: http://www.rwjhamilton.org/Atoz/Encyclopedia/article/002509.asp